Overview

Baize, a web-based software tool for rapid evaluation of sample contamination in three critical dimensions: platelet contamination, erythrocyte lysis, and residual coagulation protein carryover. The algorithm calculates cell-type-specific contamination indices by normalizing the summed intensity of marker proteins against the total intensity of plasma proteome (Contamination Index = Marker Protein Intensities / Σ All Plasma Protein Intensities). Users can submit a protein matrix with a sample annotation table, and then Baize will output an evaluation of contamination for every plasma sample.